Calcium Pantothenate (Vitamin B5)
CAS 137-08-6 · C₁₈H₃₂CaN₂O₁₀ · MW 476.53
The calcium salt of D-pantothenic acid — the stable, commercially preferred form of vitamin B5. Used in pharmaceutical supplements, cosmetic and haircare formulations, food fortification and animal nutrition. Chelora supplies IP, BP and USP grades with full documentation on every batch.
- IP / BP / USP grades
- D- and DL- forms
- Non-hazardous transport
≥ 97 %
Assay purity
CAS number
137-08-6
Melting point
~195 °C (dec.)
Pharmacopoeia
IP · BP · USP
Transport
Non-DG
Product overview
The stable salt of pantothenic acid for global nutrition
Calcium pantothenate is the calcium salt of D-pantothenic acid (vitamin B5), one of the eight essential B-complex vitamins. Because free pantothenic acid is an unstable, hygroscopic oil, it is commercially supplied and formulated as its calcium salt — a white to slightly yellow crystalline powder that is freely soluble in water and stable under normal storage conditions.
Pantothenic acid is the biosynthetic precursor to coenzyme A (CoA), a central cofactor in over 70 enzymatic pathways including fatty acid synthesis and oxidation, the citric acid cycle, acetylation reactions and steroid hormone biosynthesis. It is essential for energy metabolism, and its deficiency — though rare — leads to fatigue, irritability, numbness and gastrointestinal disturbance.
The D-isomer is the only biologically active form of pantothenic acid. Commercial calcium pantothenate for pharmaceutical, food and cosmetic use is exclusively the D-form. A racemic DL-calcium pantothenate is available at lower cost for animal feed applications, where only the D-component contributes to vitamin activity (the L-isomer is biologically inert and is excreted unchanged).
Chelora Pharmachem supplies D-calcium pantothenate in pharmacopoeia grades (IP, BP, USP) for pharma and cosmetics, as well as D- and DL- feed grades, with batch-specific COA and full regulatory documentation.
Technical specifications
Applications & end uses
Industries that depend on Calcium Pantothenate
Vitamin B5 dietary supplements
Calcium pantothenate is the standard commercial form of vitamin B5 used in tablets, capsules, multivitamin blends and B-complex formulations. As the calcium salt, it offers superior stability and handling properties compared to free pantothenic acid.
Cosmetic & haircare active
Calcium pantothenate is the precursor to panthenol (provitamin B5), a cornerstone moisturising and conditioning agent in cosmetics. It is used in shampoos, conditioners, skin creams, hair serums and leave-on treatments for hydration, elasticity and barrier repair.
Animal nutrition & feed premixes
D-Calcium pantothenate is an essential B-vitamin additive in poultry, swine, aquaculture and ruminant feed premixes. It supports growth performance, feathering, reproduction and disease resistance. DL-calcium pantothenate (racemic) is also used in cost-sensitive feed applications.
Food fortification
Calcium pantothenate fortifies breakfast cereals, beverages, dairy products and infant formula as part of B-vitamin enrichment programmes. Its good water solubility and neutral taste make it easy to incorporate in processed food matrices.
Wound healing & dexpanthenol conversion
In the body, pantothenic acid is reduced to panthenol and then oxidised to pantothenic acid at the tissue level. Topical dexpanthenol (D-panthenol) — derived from calcium pantothenate — accelerates wound healing, reduces inflammation and supports skin regeneration in dermatology.
Coenzyme A biosynthesis
Pantothenic acid is the biosynthetic precursor to coenzyme A (CoA), a central cofactor in fatty acid metabolism, the citric acid cycle and acetylation reactions. Calcium pantothenate is used in metabolic research and enzymatic assay design.
Available grades
D-form and DL-form grades
The D-isomer is the biologically active form of pantothenic acid and is required for all pharmaceutical, cosmetic and food applications. The racemic DL-form (50 % D + 50 % L) is available at lower cost for animal feed where only the D-component has vitamin activity.
≥ 99.0 %
D-Calcium Pantothenate Pharma (IP / BP / USP)
Oral and injectable vitamin supplements, cosmetics
≥ 98.0 %
D-Calcium Pantothenate Feed grade
Poultry, swine, aquaculture feed premixes
≥ 98.0 %
DL-Calcium Pantothenate (racemic)
Cost-effective feed applications (feed grade only)
Packaging options
Moisture-sealed to protect a hygroscopic material
25 kg — HDPE-lined fibre drum
Standard pharmaceutical unit; moisture-barrier sealed
20 kg — Multiwall paper bag with PE liner
Feed-grade and food-fortification supply
Sample — Sealed HDPE container
QC evaluation before commitment
Documentation supplied
Complete paperwork for QC and regulatory
Certificate of Analysis (COA)
Batch-specific results for assay, specific rotation, pH, LOD, heavy metals, nitrogen and calcium content.
Safety Data Sheet (SDS)
GHS-format, 16-section SDS covering handling, first aid, fire-fighting and disposal.
Specification sheet
Limit values for each test parameter aligned to IP, BP or USP monograph.
Pharmacopoeia compliance statement
Confirmation of monograph compliance where applicable (IP / BP / USP).
Frequently asked questions
Common questions about Calcium Pantothenate
What is the difference between D-Calcium Pantothenate and DL-Calcium Pantothenate?+
Which pharmacopoeia grades does Chelora supply?+
Is Calcium Pantothenate hygroscopic?+
What is the typical lead time for bulk orders?+
Can Calcium Pantothenate be used in cosmetic formulations?+
Do you offer samples before bulk purchase?+
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